Chirality in planar cell shape contributes to left-right asymmetric epithelial morphogenesis

Kiichiro Taniguchi1, Reo Maeda, Tadashi Ando

  • 1Department of Biological Science and Technology, Tokyo University of Science, 2641 Yamazaki, Noda, Chiba 278-8510, Japan.

Science (New York, N.Y.)
|July 19, 2011
PubMed
Summary

Animal organs show left-right asymmetry. In Drosophila, planar cell-shape chirality (PCC) drives hindgut rotation, revealing intrinsic cell chirality as a key mechanism in asymmetric tissue development.

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