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Updated: May 30, 2026

Anterior High-Resolution Optical Coherence Tomography in the Diagnosis and Therapeutic Monitoring of Ocular Surface Squamous Neoplasia
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Malherbe's Calcifying Epithelioma (Pilomatrixoma): An Uncommon Periocular Tumor
Mohammad Javed Ali1, Santosh G Honavar, Milind N Naik
1Ocular Oncology Service, L. V. Prasad Eye Institute, Banjara Hills, Hyderabad, Andhra Pradesh, India.
Abstract:
Benign calcifying epithelioma of Malherbe or pilomatrixoma or pilomatricoma is an uncommon lesion of the periocular tissues, arising from the matrix cells at the base of the hair. In the periocular area, it usually arises from the lids and eyebrows. Pilomatrixoma has certain characteristic clinical and histopathologic features, but since it is not commonly suspected preoperatively, certain distinctive clinical features of tumor should suggest clinical diagnosis followed by histopathologic confirmation.
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