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Serotonin syndrome in a postoperative patient
Minati Choudhury1, Milind P Hote, Yashwant Verma
1Department of Cardiac Anaesthesia, Cardiothoracic Sciences Centre, AIIMS, New Delhi -110 029, India.
Journal of Anaesthesiology, Clinical Pharmacology
|July 21, 2011
Summary
Depression is common in patients with ischemic heart disease. A case of serotonin syndrome occurred post-coronary artery bypass grafting due to concealed fluoxetine use, highlighting the need for thorough patient history.
Area of Science:
- Cardiology
- Psychiatry
- Pharmacology
Background:
- Depression frequently affects patients with ischemic heart disease, impacting treatment adherence.
- Stigma surrounding mental health often leads to patients withholding treatment information.
Observation:
- A patient developed serotonin syndrome post-coronary artery bypass grafting.
- The patient had been taking fluoxetine for four years, information concealed preoperatively.
Findings:
- This is the first reported case of serotonin syndrome in a postoperative patient in biomedical literature.
- Concealed antidepressant use can lead to severe adverse drug events.
Implications:
- Physicians should inquire about antidepressant use during preoperative evaluations for cardiac patients.
- Prompt recognition and management of serotonin syndrome are crucial to prevent mortality in this population.
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