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Updated: May 30, 2026

Amide Coupling Reaction for the Synthesis of Bispyridine-based Ligands and Their Complexation to Platinum as Dinuclear Anticancer Agents
07:20

Amide Coupling Reaction for the Synthesis of Bispyridine-based Ligands and Their Complexation to Platinum as Dinuclear Anticancer Agents

Published on: May 28, 2014

Supramolecular self-assembly of amphiphilic anionic platinum(II) complexes: a correlation between spectroscopic and

Charlotte Po1, Anthony Yiu-Yan Tam, Keith Man-Chung Wong

  • 1Institute of Molecular Functional Materials (Areas of Excellence Scheme, University Grants Committee (Hong Kong)), The University of Hong Kong, Pokfulam Road, Hong Kong.

Journal of the American Chemical Society
|July 22, 2011
PubMed

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Valence Bond Theory02:42

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Coordination compounds and complexes exhibit different colors, geometries, and magnetic behavior, depending on the metal atom/ion and ligands from which they are composed. In an attempt to explain the bonding and structure of coordination complexes, Linus Pauling proposed the valence bond theory, or VBT, using the concepts of hybridization and the overlapping of the atomic orbitals. According to VBT, the central metal atom or ion (Lewis acid) hybridizes to provide empty orbitals of suitable...