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Updated: May 30, 2026

Hyperpolarized Xenon for NMR and MRI Applications
Published on: September 6, 2012
NMR at earth's magnetic field using para-hydrogen induced polarization
Bob C Hamans1, Anna Andreychenko, Arend Heerschap
1Department of Radiology, Radboud University Nijmegen Medical Centre, Geert Grooteplein 10, 6525 GA Nijmegen, The Netherlands. b.hamans@rad.umcn.nl
Abstract:
A method to achieve NMR of dilute samples in the earth's magnetic field by applying para-hydrogen induced polarization is presented. Maximum achievable polarization enhancements were calculated by numerically simulating the experiment and compared to the experimental results and to the thermal equilibrium in the earth's magnetic field. Simultaneous 19F and 1H NMR detection on a sub-milliliter sample of a fluorinated alkyne at millimolar concentration (∼10(18) nuclear spins) was realized with just one single scan. A highly resolved spectrum with a signal/noise ratio higher than 50:1 was obtained without using an auxiliary magnet or any form of radio frequency shielding.
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