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[Current knowledge about pathogenesis and treatment of arterial hypertension in rheumatoid arthritis]

D S Novikova, T V Popkova, E L Nasonov

    Terapevticheskii Arkhiv
    |July 26, 2011
    PubMed

    Insights

    Rheumatoid arthritis (RA) patients face a higher risk of cardiovascular diseases (CVD), particularly arterial hypertension (AH). Understanding inflammation and drug effects is key to managing AH in RA.

    Area of Science:

    • Rheumatology
    • Cardiology
    • Immunology

    Context:

    • Rheumatoid arthritis (RA) is a chronic autoimmune condition.
    • RA patients exhibit a significantly elevated risk of cardiovascular diseases (CVD).
    • Conventional CVD risk factors like arterial hypertension (AH) and dyslipidemia are prevalent in RA.

    Purpose:

    • To explore the causes of high arterial hypertension (AH) prevalence in rheumatoid arthritis (RA) patients.
    • To examine the influence of chronic inflammation on AH development in RA.
    • To assess the impact of antirheumatic drugs with potential hypertensive effects.

    Summary:

    • The high prevalence of arterial hypertension (AH) in rheumatoid arthritis (RA) is multifactorial.
    • Chronic inflammation plays a crucial role in the development of AH in RA.
    • Antirheumatic medications can influence blood pressure, contributing to AH risk.

    Impact:

    • Provides insights into the complex relationship between RA and cardiovascular health.
    • Highlights the need for vigilant monitoring and management of AH in RA patients.
    • Offers recommendations for the prevention and treatment of AH tailored to RA individuals.

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