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Related Concept Videos

Imaging Studies II: Positron Emission Tomography and Scintigraphy01:25

Imaging Studies II: Positron Emission Tomography and Scintigraphy

Positron Emission Tomography (PET) is a medical imaging technique that provides crucial insights into the body's physiological functions at a molecular level. It is an indispensable resource for diagnosing, staging, and monitoring various illnesses, notably cancer, neurological disorders, and cardiovascular conditions.
Fundamental Principles of PET
Positron Emission Tomography01:29

Positron Emission Tomography

Positron emission tomography (PET) is a medical imaging technique involving radiopharmaceuticals — substances that emit short-lived radiation. Although the first PET scanner was introduced in 1961, it took 15 more years before radiopharmaceuticals were combined with the technique and revolutionized its potential.
One of the main requirements of a PET scan is a positron-emitting radioisotope, which is produced in a cyclotron and then attached to a substance used by the part of the body being...
Radiological Investigation III: Pulmonary Angiogram and PET Scan01:13

Radiological Investigation III: Pulmonary Angiogram and PET Scan

Radiological investigations are paramount in the diagnosis and management of various pulmonary diseases. Two essential investigations are the Pulmonary Angiogram and the Positron Emission Tomography (PET) Scan.
Pulmonary Angiogram
A Pulmonary Angiogram is an invasive procedure involving injecting a contrast medium through a catheter threaded into the pulmonary artery or the right side of the heart to visualize the pulmonary vasculature. Computed Tomography (CT) scans have mainly replaced this...
Radiological Investigation I: X-ray and CT01:30

Radiological Investigation I: X-ray and CT

Radiological investigations, including X-rays and computed tomography (CT) scans, are critical for diagnosing and evaluating various medical conditions. These imaging techniques provide valuable insights into the body's internal structures, aiding in the detection of abnormalities, assessment of disease progression, and development of treatment strategies. This article delves into two primary radiological investigations, chest X-rays and CT scans, outlining their purpose, procedures, and the...
Imaging Studies VII: Vascular Imaging01:19

Imaging Studies VII: Vascular Imaging

DefinitionRenal angiography, also known as renal arteriography, is an imaging technique used to obtain a comprehensive view of blood flow and the vascular structure of blood vessels in the kidneys and surrounding areas.PurposeRenal angiography detects blood vessel abnormalities in the kidneys, such as aneurysms, stenosis, thrombosis, vascular tumors, and renal artery stenosis. It evaluates kidney function and guides interventional treatments like angioplasty or stent placement.Pre-Procedure...

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Related Experiment Video

Updated: May 30, 2026

Enhancing Efficiency and Radiolabeling Yields of Carbon-11 Radioligands for Clinical Research Using the Loop Method
09:08

Enhancing Efficiency and Radiolabeling Yields of Carbon-11 Radioligands for Clinical Research Using the Loop Method

Published on: December 20, 2024

Molecular theranostics: a primer for the imaging professional.

Daniel Y Lee1, King C P Li

  • 1Department of Radiology, Nuclear Medicine Division, The Methodist Hospital Research Institute, 6565 Fannin St, MB1-066, Houston, TX 77030, USA. dlee@tmhs.org

AJR. American Journal of Roentgenology
|July 26, 2011
PubMed
Summary

Molecular theranostics combines diagnostic imaging with targeted therapies to detect molecular targets for precise treatment. Nanomedicines offer a versatile platform for both drug discovery and clinical applications in this emerging field.

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Area of Science:

  • Nuclear medicine
  • Molecular imaging
  • Nanomedicine

Background:

  • Theranostic systems integrate diagnostic testing with targeted drug delivery.
  • Molecular imaging enables noninvasive disease detection by identifying molecular targets.
  • Nuclear medicine has established foundational paradigms for theranostics.

Purpose of the Study:

  • To review existing paradigms in molecular imaging for theranostics.
  • To highlight recent advancements in molecular imaging and theranostic platforms.
  • To explore the potential of nanomedicines as theranostic platforms.

Main Methods:

  • Review of nuclear medicine principles and practices.
  • Analysis of recent advancements in molecular imaging techniques.
  • Exploration of nanomedicine applications in theranostics.

Main Results:

  • Molecular imaging provides essential diagnostic information for theranostics.
  • Nanomedicines demonstrate significant potential as theranostic platforms.
  • Theranostics enables targeted therapy guided by molecular imaging.

Conclusions:

  • Molecular theranostics is a powerful emerging platform.
  • It couples targeted therapeutics with noninvasive imaging.
  • Provides crucial information on molecular targets before, during, and after therapy.