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Deleterious effect of anti-insulin antibodies on diabetes control
A Livneh1, H Avraham, T Bistritzer
1Department of Medicine, Chaim Sheba Medical Center, Tel-Hashomer, Israel.
Israel Journal of Medical Sciences
|January 1, 1990
Abstract:
We studied the effect of anti-insulin antibodies (AIA) on glycemia control in patients with insulin-dependent diabetes (IDD) by following the AIA titer changes with time. Although expected to remain constant, AIA levels were found to either increase or decrease in most patients. These AIA titer changes correlated significantly with changes in glycohemoglobin but not with changes in insulin dose. The results suggest that AIA may have a deleterious effect on glycemia control in IDD.