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Updated: May 30, 2026

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Microfluidic Synthesis of Microgel Building Blocks for Microporous Annealed Particle Scaffold
Published on: June 16, 2022
Double emulsions with controlled morphology by microgel scaffolding.
Julian Thiele1, Sebastian Seiffert
1Physical Chemistry I, Bayreuth University, Universitätsstrasse 30, D-95447, Bayreuth, Germany. julian.thiele@uni-bayreuth.de
Lab on a Chip
|July 29, 2011
Summary
Researchers used microfluidics to create stable, non-spherical double emulsions by incorporating microgel particles. This method precisely controls droplet morphology without needing rapid polymerization or confinement.
Area of Science:
- Materials Science
- Chemical Engineering
- Colloid and Surface Chemistry
Background:
- Double emulsions, with nested droplet structures, are formed using microfluidics, enabling control over size and composition.
- Controlling the equilibrium morphology of deformable double emulsions is challenging due to thermal fluctuations.
Purpose of the Study:
- To develop a method for controlling the morphology of double emulsions.
- To arrest the shape of double emulsions, creating uniform, anisotropic structures.
Main Methods:
- Utilized droplet-based microfluidics to generate oil-in-water-in-oil double emulsion drops.
- Incorporated monodisperse microgel particles into the emulsion drops to arrest their shape.
- Analyzed the resulting arrested, anisotropic double emulsion morphology.
Main Results:
- Microgel particles induced the inner oil drop to migrate to the edge of the aqueous shell.
- This resulted in uniformly arrested, anisotropic double emulsion shapes.
- The technique successfully synthesized anisotropic polyacrylate-polyacrylamide microparticles with controlled size and shape.
Conclusions:
- This microfluidic approach with microgel particles provides precise control over double emulsion morphology.
- It circumvents the need for rapid polymerization or geometric confinement to achieve non-spherical droplet shapes.
- The method is effective for synthesizing tailored anisotropic microparticles.

