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Updated: May 30, 2026

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A Quantitative Sensory Testing Paradigm to Obtain Measures of Pain Processing in Patients Undergoing Breast Cancer Surgery
Published on: January 18, 2018
Verification of nerve integrity after surgical intervention using quantitative sensory testing.
Sareh Said-Yekta1, Ralf Smeets, Marcella Esteves-Oliveira
1Department of Conservative Dentistry, Periodontology and Preventive Dentistry, Aachen University, Aachen, Germany. ssaidyekta@izkf.rwth-aachen.de
Summary
Oral surgery can cause hidden sensory deficits in the mental and lingual nerves, even without patient-reported symptoms. Quantitative Sensory Testing (QST) effectively detects these changes and monitors recovery.
Area of Science:
- Oral surgery
- Neuroscience
- Sensory testing
Background:
- Oral surgery can potentially cause sensory alterations.
- Patients may not report subjective sensory disturbances.
- Objective assessment of trigeminal nerve function is crucial.
Purpose of the Study:
- To investigate sensory changes after oral surgery using Quantitative Sensory Testing (QST).
- To determine the degree and duration of neuronal hyperexcitability post-surgery.
- To assess if QST can detect subclinical sensory alterations.
Main Methods:
- QST was applied to 60 patients undergoing oral surgery.
- Sensory functions were tested in infraorbital, mental, and lingual nerve areas.
- Testing occurred at 1, 4, 7, and 10 weeks post-operation, with controls included.
Main Results:
- No sensory differences were found between controls and patient control sides.
- QST revealed significant sensory deficits in mental and lingual regions, despite no reported symptoms.
- Reduced sensitivity to thermal stimuli and decreased pain pressure thresholds were observed on operated sides.
Conclusions:
- Oral surgery can induce subclinical sensory deficits in the mental and lingual regions.
- QST is a valuable tool for objectively assessing trigeminal nerve function post-surgery.
- QST can objectify clinical findings, particularly in forensic contexts.

