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Updated: May 30, 2026
09:09
Description of a Swine Infant Model of Volume-Controlled Hemorrhagic Shock
Published on: November 3, 2023
[Postpartum hemorrhage--an update]
1Klinik für Anästhesiologie und operative Intensivmedizin am Klinikum Harlaching in München. wiebke.gogarten@klinikum-muenchen.de
Summary
Postpartum hemorrhage (PPH) management requires prompt action, including uterotonics and early clotting factor optimization. Tranexamic acid and fibrinogen are key, followed by blood products if bleeding persists.
Area of Science:
- Obstetrics and Gynecology
- Maternal Health
- Hemorrhage Management
Context:
- Postpartum hemorrhage (PPH) is a leading cause of maternal mortality globally.
- Increasing incidence linked to higher rates of placenta accreta/percreta post-Cesarean delivery.
- Developed countries observe a rise in PPH cases.
Purpose:
- To outline current best practices for managing postpartum hemorrhage.
- To emphasize early intervention and optimization of coagulation.
- To highlight the importance of standardized protocols and drills.
Summary:
- Initial PPH management involves uterotonic drugs and uterine cavity inspection.
- Early optimization of clotting potential is crucial, considering tranexamic acid first-line.
- If bleeding continues, fibrinogen, fresh frozen plasma, and packed red cells (1:1 ratio) are indicated.
- Standard operating procedures and regular drills are essential for all labor and delivery units.
Impact:
- Improved maternal outcomes through timely and evidence-based PPH management.
- Reduced maternal morbidity and mortality associated with postpartum hemorrhage.
- Enhanced preparedness of healthcare facilities for obstetric emergencies.
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