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Updated: May 30, 2026
11:47
Residue-specific Incorporation of Noncanonical Amino Acids into Model Proteins Using an Escherichia coli Cell-free Transcription-translation System
Published on: August 1, 2016
Expanding the genetic code of an animal
Sebastian Greiss1, Jason W Chin
1Medical Research Council Laboratory of Molecular Biology, Hills Road, Cambridge, CB2 0QH, UK.
Journal of the American Chemical Society
|August 9, 2011
Abstract
None:
Genetic code expansion, for the site-specific incorporation of unnatural amino acids into proteins, is currently limited to cultured cells and unicellular organisms. Here we expand the genetic code of a multicellular animal, the nematode Caenorhabditis elegans.
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