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Updated: May 30, 2026

A Customizable Approach for the Enzymatic Production and Purification of Diterpenoid Natural Products
Published on: October 4, 2019
New triterpene oligoglycosides from the Caribbean sponge Erylus formosus
Alexandr S Antonov1, Anatoly I Kalinovsky, Pavel S Dmitrenok
1Pacific Institute of Bioorganic Chemistry, Far East Division of the Russian Academy of Science, 690022 Vladivostok, Russia.
Abstract:
Seven new triterpene glycosides, erylosides R(1) (1), T(1) (3), T(2) (4), T(3) (5), T(4) (6), T(5) (7), and T(6) (8) along with the known formoside (2) were isolated from the sponge Erylus formosus collected along the Caribbean coast of Mexico. Glycoside 1 was determined as a trisaccharide, glycoside 2 as a tetrasaccharide while glycosides 3-8 were hexasaccharide. Their carbohydrate chains were unprecedented and have never been found in oligosaccharides from other biological sources, except Erylus spp. Three carbohydrate chains in the glycosides 3 and 6, 4 and 7, 5 and 8 correspondingly are new. The glycosides 1-5 have penasterol as aglycone while glycosides 6-8 proved to be glycoconjugates of 24-methylene-14-carboxy-lanost-8(9)-en-3β-ol.
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