Related Experiment Video
Updated: May 30, 2026

Developing a Rat Model for Bipolar Disorder
Published on: May 2, 2025
Treatment of Pediatric Bipolar Disorder: A Review
Jason J Washburn1, Amy E West, Jennifer A Heil
1Northwestern University Feinberg School of Medicine, Department of Psychiatry and Behavioral Sciences.
None:
AIM: To review the diagnosis and the pharmacologic and psychosocial interventions for pediatric bipolar disorder (PBD). METHODS: A comprehensive literature review of studies discussing the diagnosis and treatment of PBD was conducted. RESULTS: A context for understanding controversies and difficulties in the diagnosis of PBD is provided. An evidence-based assessment protocol for PBD is reviewed. The evidence for the following three categories of pharmacologic interventions are reviewed: Lithium, antiepileptics, and second generation antipsychotics. Algorithms for medication decisions are briefly reviewed. Existing psychosocial treatments and the evidence for those treatments are also reviewed. CONCLUSION: Despite recent developments in understanding the phenomenology of PBD and in identifying pharmacologic and psychosocial interventions, critical gaps remain.
Related Concept Videos
Mania and Antimanic Drugs: Overview
Bipolar Disorder
Psychosis: Goals of Pharmacotherapy
Pharmacokinetics in Pediatric Patients: Drug Metabolism
Drug Therapy
Antianxiety Medications
Treatment Strategies for Psychological Disorders
Psychological therapies focus on modifying emotions, thoughts, and behaviors through talking, interpreting, listening, rewarding, challenging, and modeling. Clinical psychologists, counselors, and social workers commonly practice psychotherapy. Clinical...