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Updated: May 30, 2026
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Aptamer-Based Target Detection Facilitated by a 3-Stage G-Quadruplex Isothermal Exponential Amplification Reaction
Published on: October 6, 2022
An ultrasensitive peroxidase DNAzyme-associated aptasensor that utilizes a target-triggered enzymatic signal
Rongzhan Fu1, Kyungeun Jeon, Cheulhee Jung
1Department of Chemical and Biomolecular Engineering (BK21 Program), KAIST, Yuseong-gu, Daejeon, Republic of Korea.
Chemical Communications (Cambridge, England)
|August 10, 2011
Abstract:
By rationally employing enzymes for signal amplification, an ultrasensitive aptasensor was developed and successfully tested in a system designed to detect lysozyme with a detection limit of 0.1 fM. This detection limit is nearly three orders of magnitude lower than those of any previously reported DNAzyme-based aptasensors.
