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Related Concept Videos

Yellow Fever01:18

Yellow Fever

Yellow fever is a viral hemorrhagic disease caused by the yellow fever virus (YFV), a member of the Flaviviridae family. It is transmitted primarily by Aedes and Haemagogus mosquitoes in tropical and subtropical regions of Africa and South America. After transmission through a mosquito bite, the virus initially replicates in skin-resident immune cells such as dendritic cells and macrophages. These cells then migrate to the lymph nodes, where viral replication increases, eventually leading to...
Arboviral Encephalitis01:25

Arboviral Encephalitis

Arboviral encephalitis refers to brain inflammation caused by arthropod-borne viruses, particularly those transmitted through mosquito vectors. Among these, West Nile virus (WNV), a member of the Flaviviridae family, is a significant public health concern. WNV is an enveloped, positive-sense, single-stranded RNA virus. Human infection typically begins when an infected mosquito introduces the virus into the dermis during feeding. The primary transmission cycle involves birds as amplifying hosts...
Malaria01:29

Malaria

Malaria pathogenesis in humans reflects a delicate interplay between parasite biology and host response. Clinical illness reflects a host’s immune response to the parasite’s asexual replication cycle, which is often asymptomatic in individuals with partial immunity. From the parasite's perspective, transmission between mosquito and human with minimal host pathology is evolutionarily advantageous. Among the six Plasmodium species infecting humans, P. falciparum and P. vivax dominate in global...
Infectious Diseases and Their Occurrence01:28

Infectious Diseases and Their Occurrence

Infectious diseases appear in populations through various transmission patterns, influenced by pathogen characteristics, population immunity, environmental conditions, and social behavior. Understanding these patterns is essential for effective public health surveillance and intervention. These categories—sporadic, outbreak, epidemic, pandemic, and endemic—help frame the nature and scope of disease events.Sporadic diseases occur irregularly and infrequently, without a predictable temporal or...
Classification of Illness01:17

Classification of Illness

The meaning of illness is individualized to each person who experiences an alteration in health. In contrast, disease is a medical term indicating a pathological change in the structure and function of the body or mind. It is a condition that has specific symptoms and boundaries.
An illness is a response to a disease in which the person's level of functioning is changed compared with a previous level. The general classification of illness includes acute and chronic.
Acute illness is severe and...
Patterns of Fever01:26

Patterns of Fever

Before understanding the types and patterns of fever, it is essential to know its phases.

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Related Experiment Video

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Measuring Dengue Virus RNA in the Culture Supernatant of Infected Cells by Real-time Quantitative Polymerase Chain Reaction
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Measuring Dengue Virus RNA in the Culture Supernatant of Infected Cells by Real-time Quantitative Polymerase Chain Reaction

Published on: November 1, 2018

Dengue--how best to classify it.

Anon Srikiatkhachorn1, Alan L Rothman, Robert V Gibbons

  • 1Department of Medicine, University of Massachusetts Medical School, Worcester, Massachusetts 01655, USA. anon.srikiatkhachorn@umassmed.edu

Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America
|August 12, 2011
PubMed
Summary
This summary is machine-generated.

The World Health Organization updated its dengue classification in 2009 from dengue fever and dengue hemorrhagic fever to dengue and severe dengue. This new system impacts clinical practice, research, and public health policy.

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Measuring Dengue Virus RNA in the Culture Supernatant of Infected Cells by Real-time Quantitative Polymerase Chain Reaction
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Portable Paper-Based Immunoassay Combined with Smartphone Application for Colorimetric and Quantitative Detection of Dengue NS1 Antigen

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Area of Science:

  • Public Health
  • Infectious Diseases
  • Virology

Background:

  • Dengue virus infection is a significant global health concern with diverse clinical presentations.
  • Previous World Health Organization (WHO) dengue classification (1970s) included dengue fever and dengue hemorrhagic fever.
  • This older classification faced criticism regarding its clinical utility and applicability.

Purpose of the Study:

  • To analyze the shift in dengue classification by the WHO in 2009.
  • To evaluate the implications of the new classification system on clinical management, scientific research, and public health strategies.
  • To discuss the conceptual and practical differences between the 2009 and earlier WHO dengue classifications.

Main Methods:

  • Review of World Health Organization guidelines and dengue classification systems.
  • Analysis of the conceptual and practical differences between the 1970s and 2009 classifications.
  • Discussion of the impact of the revised classification on dengue management and research.

Main Results:

  • The 2009 WHO guideline introduced a revised classification: dengue and severe dengue.
  • This new classification represents a significant departure from the previous system.
  • The updated system aims to improve the diagnosis and management of dengue cases.

Conclusions:

  • The 2009 WHO dengue classification offers a more refined approach to clinical diagnosis.
  • The new system has substantial implications for clinical practice, dengue research, and public health policy.
  • Effective implementation of the 2009 classification is crucial for global dengue control efforts.