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Bioactivities of Chuquiraga straminea sandwith
María Elena Mendiondo1, Berta E Juáreza, Catiana Zampini
1Facultad de Ciencias Naturales e Instituto Miguel Lillo, UNT, Fundación Miguel Lillo, CONICET Miguel Lillo 205/251, (4000) San Miguel de Tucumán, Tucumán, Argentina.
Abstract:
Methanolic extracts of Chuquiraga straminea Sandwith, subfamily Barnadesioideae (Asteraceae) showed the presence of quercetin-3-O-glucoside, quercetin-3-O-rutinoside, kaempferol, kaempferol-3-O-glucoside and kaempferol-3-O-rutinoside. Antioxidant and antimicrobial activity was determined. The total extracts showed antioxidant activity by DPPH and ABTS method (SC50 14.5 to 34.9 microg/mL). A significantly positive correlation was observed between the antioxidant activity and the total phenolics (R2 > 0.93). The extracts were active against ten methicillin resistant and sensitive Staphylococcus aureus strains isolated from nosocomial infection (MIC values between 200 to 800 microg/mL). These preliminary studies are highly interesting as they open new ways for further applications in the treatment of infections by methicillin resistant S. aureus.
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