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Updated: May 30, 2026

Fertility Preservation Through Oocyte Vitrification: Clinical and Laboratory Perspectives
Published on: September 16, 2021
[Oocyte/embryo cryopreservation before chemotherapy for breast cancer]
1Service d'AMP de l'hôpital Jeanne-de-Flandre, centre de préservation ovarienne, CHRU de Lille, rue Eugène-Avinée, Lille cedex, France. christine.decanter@chru-lille.fr
Abstract:
Breast cancer affects 6300 new patients per year under age 40 per year in France. The new adjuvant chemotherapy protocols have significantly improved the prognosis of these young women who may wish to conceive later. Embryo cryopreservation is the best way to preserve fertility, providing 25 to 35% chance of pregnancy. Oocyte freezing may be an alternative for single patients. This review will focus on: (1) ovarian toxicity of new adjuvant chemotherapy protocols, (2) the place of embryo or oocyte cryopreservation in fertility preservation techniques, (3) indications and protocols.
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