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Bilateral multiple extraocular muscle metastasis from breast carcinoma
Ramesh Murthy1, Amit Gupta, Sunayana Hegde
1Department of Pediatric Ophthalmology and Strabismus and Oculoplasty, Ocular Oncology, and Orbit, L. V. Prasad Eye Institute, L. V. Prasad Marg, Banjara Hills, Hyderabad - 500 073, India. drrameshmurthy@gmail.com
This case study highlights a rare instance of breast cancer metastasizing to eye muscles, initially mistaken for a pseudotumor. Prompt diagnosis and treatment led to complete remission, emphasizing the importance of considering metastasis in similar presentations.
Area of Science:
- Oncology
- Ophthalmology
- Pathology
Background:
- Metastatic disease to the orbit is uncommon.
- Lobular carcinoma of the breast is known for its diverse metastatic patterns.
Observation:
- A 61-year-old female presented with external ophthalmoplegia and diplopia, initially diagnosed as a pseudotumor.
- Histopathology revealed bilateral breast metastases of lobular carcinoma involving multiple extraocular muscles.
Findings:
- The patient underwent incisional biopsy, radiotherapy, and hormonal therapy.
- Complete remission was achieved after 18 months of hormonal therapy, with improved ocular motility and resolved diplopia.
Implications:
- Extraocular muscle involvement by breast carcinoma metastasis is a rare entity.
- This diagnosis should be considered in patients with a history of breast carcinoma presenting with ophthalmoplegia.
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