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Helichrysum monizii Lowe: phenolic composition and antioxidant potential
Sandra Gouveia1, Paula C Castilho
1Centro de Química da Madeira, CCCEE, Universidade da Madeiram, Campus da Penteada, 9000-390, Funchal, Portugal.
Phytochemical Analysis : PCA
|August 13, 2011
Summary
Helichrysum monizii, a rare plant from Madeira, exhibits significant antioxidant potential. Dicaffeoylquinic acids were identified as the primary compounds responsible for this activity, establishing its medicinal value.
Area of Science:
- Phytochemistry
- Pharmacognosy
- Medicinal Botany
Background:
- Madeira Archipelago hosts four endemic Helichrysum species, with three utilized in traditional medicine.
- Helichrysum monizii is a rare endemic species with limited documented traditional medicinal uses.
Purpose of the Study:
- To investigate the antioxidant capacity of Helichrysum monizii for the first time.
- To identify the specific phenolic compounds contributing to its antioxidant activity.
Main Methods:
- Extraction using three different methods.
- Quantification of total phenolic and flavonoid content.
- Assessing antioxidant capacity via DPPH, ABTS, FRAP, and β-carotene assays.
- Utilizing HPLC-DAD-ESI/MS(n) for phenolic compound identification.
Main Results:
- A high antioxidant potential was observed, primarily linked to the plant's phenolic profile.
- Methanol extracts revealed polar components, including 33 identified compounds.
- Nineteen of the identified compounds were characterized as quinic acid derivatives.
Conclusions:
- The significant antioxidant potential of Helichrysum monizii has been established.
- Dicaffeoylquinic acids are the principal contributors to the plant's antioxidant activity.
