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In Vitro Selection of Aptamers to Differentiate Infectious from Non-Infectious Viruses
Published on: September 7, 2022
[Aptamers: characteristics and applications in pathogenic microorganism]
Hongru Liang1, Songtao Yang, Tao Zhang
1College of Animal Science and Veterinary, Jilin University, Changchun 130062, China.
Sheng Wu Gong Cheng Xue Bao = Chinese Journal of Biotechnology
|August 18, 2011
Summary
Artificial oligonucleotides called aptamers, identified via SELEX technology, offer versatile applications in basic research, diagnostics, and nanotechnology, particularly in medical microbiology.
Area of Science:
- Biochemistry and Molecular Biology
- Biotechnology
Context:
- Aptamers are artificial nucleic acid or peptide molecules.
- They are selected using a process called SELEX (Systematic Evolution of Ligands by Exponential Enrichment).
- Aptamers have diverse applications in research, diagnostics, and nanotechnology.
Purpose:
- To introduce the technology behind aptamer development.
- To summarize the applications of aptamers in the field of medical microbiology.
Summary:
- Aptamers are synthesized oligonucleotides identified through SELEX.
- This technology enables the selection of high-affinity binding molecules.
- The article focuses on aptamer applications within medical microbiology.
Impact:
- Provides an overview of aptamer technology for researchers.
- Highlights the potential of aptamers in advancing medical microbiology diagnostics and therapeutics.
- Facilitates understanding of aptamer utility in various scientific domains.
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