Related Experiment Video
Updated: May 30, 2026
Echocardiographic Assessment of Cardiac Anatomy and Function in Adult Rats
Published on: December 13, 2019
Non-geometric echocardiographic indices of ventricular function in patients with a Fontan circulation
Jonathan Rhodes1, Renee Margossian, Lynn A Sleeper
1Children' Hospital Boston and Harvard Medical School, Boston, Massachusetts, USA. jonathan.rhodes@cardio.chboston.org
Background:
Complex anatomy and limited windows complicate echocardiographic assessments of ventricular function in Fontan patients. For the Pediatric Heart Network Fontan Cross-Sectional Study, data were acquired from which mean ventricular pressure change during isovolumetric contraction (dP/dt(ic)), Tei index, and maximal systolic annular velocity (S') could be measured. The purpose of this study was to compare these nongeometric indices of ventricular function to cardiac magnetic resonance (CMR) measurements of ventricular ejection fraction (EF).
Methods:
Echocardiographic and CMR studies were performed prospectively using standardized protocols; measurements were completed by core laboratories. Data from both modalities were available from 137 patients.
Results:
A weak but statistically significant correlation was observed between mean dP/dt(ic) and CMR-derived EF (r = 0.20, P = .022). This correlation was strengthened when preload was taken into account (r = 0.30, P = .001). Statistically significant correlations did not exist between CMR-derived EF and the Tei index or S'.
Conclusions:
Among Fontan patients, the correlation between CMR-derived EF and nongeometric echocardiographic indices of ventricular function is not strong. Of the indices evaluated, however, mean dP/dt(ic) appears to be the best.
More Related Videos
12:12Echocardiographic Approaches and Protocols for Comprehensive Phenotypic Characterization of Valvular Heart Disease in Mice
Published on: February 14, 2017
04:48Noninvasive Determination of Vortex Formation Time Using Transesophageal Echocardiography During Cardiac Surgery
Published on: November 28, 2018
Related Concept Videos
01:20Imaging Studies for Cardiovascular System II:Types of Echocardiography
Types of Echocardiography
Transthoracic Echocardiography (TTE)
TTE is the most common type of echocardiogram which involves placing a transducer on the patient's chest, emitting sound waves to create heart images. TTE is invaluable for evaluating the heart's size, structure, and motion, making it particularly useful for diagnosing...
01:17Imaging Studies for Cardiovascular System I:Echocardiography
Indications: Echocardiography is utilized to diagnose heart failure, valve disorders, and myocardial infarction. It also assesses cardiac structures' size, shape, and motion, evaluates...