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Updated: May 30, 2026

Microsurgical Creation of Giant Bifurcation Aneurysms in Rabbits for the Evaluation of Endovascular Devices
Published on: September 8, 2023
Comparison of coil types in aneurysm recurrence
Shah-Naz Hayat Khan1, Christopher Nichols, John J Depowell
1The University of Cincinnati (UC) Neuroscience Institute: Department of Neurosurgery, UC College of Medicine, Cincinnati, OH, United States. khan@sasktel.net
HydroCoil and bare platinum coils showed similar retreatment rates for aneurysms. HydroCoils demonstrated superior long-term occlusion and less recanalization compared to Matrix coils.
Area of Science:
- Neurosurgery
- Interventional Radiology
- Medical Devices
Background:
- Saccular aneurysm coiling can lead to recurrence and retreatment.
- Aneurysm recanalization is influenced by the type of coil used.
Purpose of the Study:
- To evaluate the effect of different coil types on aneurysm recurrence.
- Compare recurrence and recanalization rates among bare platinum, Matrix, and HydroCoil devices.
Main Methods:
- Retrospective analysis of 100 consecutive ruptured aneurysms (4-15mm) treated with coils.
- Patients were grouped by coil type: bare platinum, HydroCoil, or Matrix.
- Follow-up data included retreatments, angiographic occlusion, and recanalization.
Main Results:
- Retreatment rates were 12.1% for bare platinum, 21.9% for Matrix, and 11.5% for HydroCoil.
- HydroCoil group showed the highest complete occlusion and lowest residual aneurysms (P=0.01).
- Recanalization tendencies: Matrix (greatest), bare platinum (intermediate), HydroCoil (least).
Conclusions:
- Matrix coils had the highest retreatment rate.
- Bare platinum and HydroCoils had comparable retreatment rates.
- HydroCoils demonstrated statistically significant attenuation of residual aneurysms and the least recanalization.
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