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Related Experiment Video

Updated: May 29, 2026

Extraction of Extracellular Vesicles from Whole Tissue

Extraction of Extracellular Vesicles from Whole Tissue

Published on: February 7, 2019

Exosomes: secreted vesicles and intercellular communications.

Clotilde Théry¹

¹Institut Curie INSERM U932, Paris France.

F1000 Biology Reports

|August 31, 2011

Summary

This summary is machine-generated.

Exosomes, small vesicles involved in cell communication, have gained significant attention due to their cargo of mRNA and microRNA. This finding has spurred research into their composition, function, and biomarker potential.

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Purification and microRNA Profiling of Exosomes Derived from Blood and Culture Media

Purification and microRNA Profiling of Exosomes Derived from Blood and Culture Media

Published on: June 14, 2013

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Last Updated: May 29, 2026

Extraction of Extracellular Vesicles from Whole Tissue

Extraction of Extracellular Vesicles from Whole Tissue

Published on: February 7, 2019

Purification and microRNA Profiling of Exosomes Derived from Blood and Culture Media

Purification and microRNA Profiling of Exosomes Derived from Blood and Culture Media

Published on: June 14, 2013

Area of Science:

Cell Biology
Molecular Biology
Biochemistry

Background:

Exosomes are small, endocytic-origin membrane vesicles secreted by various cell types.
They are implicated in intercellular communication.
Initial discovery in 1983, but recent findings have dramatically increased research interest.

Purpose of the Study:

To investigate the composition and function of exosomes.
To explore the potential of exosomes as biomarkers.
To understand their role in intercellular communication.

Main Methods:

Vesicle isolation and characterization.
Analysis of exosomal content (mRNA, microRNA).
Functional assays to determine intercellular signaling roles.

Main Results:

Exosomes were confirmed to contain mRNA and microRNA.
Significant increase in research activity focusing on exosomes.
Growing evidence for their role in intercellular communication.

Conclusions:

The discovery of nucleic acids within exosomes has revitalized research in intercellular vesicle communication.
Exosomes represent a promising area for biomarker discovery.
Further research is needed to fully elucidate exosome function and therapeutic potential.