Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Video

Updated: May 29, 2026

Using an Automated Hirschberg Test App to Evaluate Ocular Alignment
05:40

Using an Automated Hirschberg Test App to Evaluate Ocular Alignment

Published on: March 24, 2020

The potential cost-effectiveness of amblyopia screening programs.

David B Rein1, John S Wittenborn, Xinzhi Zhang

  • 1NORC at the University of Chicago, 55 East Monroe St., Chicago, IL 60603, USA. rein-david@norc.org

Journal of Pediatric Ophthalmology and Strabismus
|September 1, 2011
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

The cost-effectiveness of the stopping elderly accidents, deaths and injuries options randomised quality improvement trial to prevent falls among older adults.

Age and ageing·2026
Same author

Performance of ICD-10 code-based dementia case definition in the Health and Retirement Study.

Alzheimer's & dementia : the journal of the Alzheimer's Association·2026
Same author

Protocol for a multicenter prospective sequential intervention study: the effect of adaptive closed-loop postural training on gait disorders in hemiparetic stroke patients.

Frontiers in neurology·2026
Same author

Darvadstrocel in Patients With Crohn's Disease With Complex Perianal Fistulas: The ADMIRE CD II Phase 3 Randomized Trial.

Gastroenterology·2026
Same author

Process and Outcome Evaluation of the National Institutes of Health Community Engagement Alliance.

Public health reports (Washington, D.C. : 1974)·2026
Same author

Efficacy and Safety of Subcutaneous Anifrolumab in Systemic Lupus Erythematosus: A Randomized, Phase 3 Study.

Arthritis & rheumatology (Hoboken, N.J.)·2025
Same journal

TeleROP-NI: Modernizing Retinopathy of Prematurity Screening in Northern Ireland to Enhance Decision-making and Ensure Sustainability.

Journal of pediatric ophthalmology and strabismus·2026
Same journal

Ocular Microstructural Alterations in Children With Spina Bifida: An Optical Coherence Tomography Study.

Journal of pediatric ophthalmology and strabismus·2026
Same journal

Systemic Inflammatory Markers and Their Relationship With Optic Nerve Head Alterations in Pediatric Idiopathic Intracranial Hypertension.

Journal of pediatric ophthalmology and strabismus·2026
Same journal

Evaluating Large Language Models to Improve Spanish Patient Education on Childhood Glaucoma.

Journal of pediatric ophthalmology and strabismus·2026
Same journal

Comparative Evaluation of Unilateral Recession-Plication Versus Bilateral Three-Muscle Surgery for Large-Angle Exotropia.

Journal of pediatric ophthalmology and strabismus·2026
Same journal

Long-term Visual Sequelae of Shaken Baby Syndrome: A Retrospective Study of 52 Cases.

Journal of pediatric ophthalmology and strabismus·2026
See all related articles

Early amblyopia screening (lazy eye) is cost-effective for preventing vision loss. The optimal screening strategy depends on budget and the value placed on preserving vision.

Area of Science:

  • Ophthalmology
  • Public Health
  • Health Economics

Background:

  • Amblyopia, or lazy eye, is a leading cause of preventable vision loss in children.
  • Early detection and treatment are crucial for effective management and preventing long-term visual impairment.

Purpose of the Study:

  • To compare the incremental cost-effectiveness of three amblyopia screening strategies versus no screening.
  • To evaluate screening at preschool and kindergarten using acuity/stereopsis (A/S) or photoscreening.

Main Methods:

  • A probabilistic microsimulation model was used to simulate amblyopia natural history and treatment response.
  • Costs and outcomes were estimated from state programs, calculating cost-effectiveness per quality-adjusted life year (QALY) gained and case avoided.

More Related Videos

Subjective Refraction Test Using a Smartphone for Vision Screening
05:36

Subjective Refraction Test Using a Smartphone for Vision Screening

Published on: October 18, 2024

Related Experiment Videos

Last Updated: May 29, 2026

Using an Automated Hirschberg Test App to Evaluate Ocular Alignment
05:40

Using an Automated Hirschberg Test App to Evaluate Ocular Alignment

Published on: March 24, 2020

Subjective Refraction Test Using a Smartphone for Vision Screening
05:36

Subjective Refraction Test Using a Smartphone for Vision Screening

Published on: October 18, 2024

Main Results:

  • No screening was most cost-effective at a willingness to pay (WTP) <$16,000/QALY.
  • A/S screening at kindergarten was cost-effective at WTP $17,000-$21,000.
  • Preschool/kindergarten A/S screening was cost-effective at WTP $22,000-$75,000; photoscreening at preschool + A/S at kindergarten was cost-effective at WTP >$75,000.
  • All scenarios were cost-effective at a WTP of $10,500 per case cured, with improved cost-effectiveness at higher utility loss assumptions.

Conclusions:

  • All evaluated amblyopia screening interventions are likely cost-effective compared to other public health programs.
  • The optimal screening approach depends on available funding and the societal value assigned to preventing monocular vision loss.