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Comprehensive Endovascular and Open Surgical Management of Cerebral Arteriovenous Malformations
Published on: October 20, 2017
Caring for cerebral venous sinus thrombosis in children
Mubashira Hashmi1, Mohammad Wasay
1Department of Medicine, Section of Neurology, Aga Khan University and Hospital, Stadium Road, Karachi, Pakistan.
Journal of Emergencies, Trauma, and Shock
|September 3, 2011
Summary
Pediatric cerebral venous sinus thrombosis (CVST) is a complex condition often caused by multiple risk factors. While treatments for symptoms like seizures and high intracranial pressure are standard, anticoagulation and thrombolysis remain debated.
Area of Science:
- Neurology
- Pediatrics
- Vascular Medicine
Background:
- Cerebral venous sinus thrombosis (CVST) in children is increasingly recognized due to improved diagnostics and clinical awareness.
- It is a multifactorial condition resulting from a combination of prothrombotic risk factors and predisposing clinical conditions.
- Clinical presentations vary widely, including headache, seizures, and coma.
Purpose of the Study:
- To review the current understanding of pediatric cerebral venous sinus thrombosis.
- To discuss the underlying etiologies, clinical features, and management controversies.
- To highlight the potential for significant morbidity and long-term neurological sequelae.
Main Methods:
- Review of existing literature on pediatric cerebral venous sinus thrombosis.
- Analysis of diagnostic tools and clinical awareness improvements.
- Discussion of current treatment strategies and their controversies.
Main Results:
- Improved diagnostic tools and clinical awareness have led to increased recognition of pediatric CVST.
- Etiology is multifactorial, involving prothrombotic risks and clinical conditions.
- Treatment for symptoms like intracranial hypertension is standard, but anticoagulation and thrombolysis are controversial.
Conclusions:
- Pediatric CVST requires a comprehensive understanding of its multifactorial nature.
- Management strategies, particularly anticoagulation and thrombolysis, require further investigation.
- Significant morbidity and long-term neurological deficits can occur, emphasizing the need for timely diagnosis and management.
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