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Related Concept Videos

Rabies01:28

Rabies

Rabies is a lethal zoonotic disease caused by a single-stranded, negative-sense RNA virus of the Lyssavirus genus, within the family Rhabdoviridae. Its primary mode of transmission to humans is through bites or saliva-contaminated scratches from infected mammals such as dogs, bats, raccoons, or foxes. Transmission can also occur if infectious saliva contacts abraded skin or intact mucous membranes, including the conjunctiva.Viral Entry and Early ReplicationOnce introduced at the bite or scratch...
Poliomyelitis01:17

Poliomyelitis

Poliomyelitis is caused by poliovirus, a small, non-enveloped, positive-sense RNA virus of the Picornaviridae family and Enterovirus genus. Transmission occurs primarily via the fecal-oral route, often through ingestion of contaminated water or food. The virus initially replicates in the oropharynx and intestinal mucosa, particularly in lymphoid tissues such as the tonsils, Peyer’s patches, and regional lymph nodes. Primary viremia follows, allowing dissemination throughout the body.In most...
Rab Proteins01:14

Rab Proteins

Rab proteins constitute the largest family of monomeric GTPases, of which 70 members are present in humans. Rab proteins and their effectors regulate consecutive stages of vesicle transport such as vesicle transport, docking, and fusion to the correct recipient membrane.
Rab proteins switch between a cytosolic, GDP-bound inactive state and a membrane-anchored, GTP-bound active state. By themselves, Rabs show slow rates of GDP/GTP exchange and GTP hydrolysis. Thus, Rab proteins are considered...
Size and Structure of Viral Genomes01:26

Size and Structure of Viral Genomes

Viral genomes exhibit remarkable diversity in size, structure, and composition, influencing their replication strategies and interactions with host cells. These genomes consist of either DNA or RNA and may be linear or circular. Additionally, they can be single-stranded or double-stranded, with each configuration affecting how the virus propagates within a host. RNA viruses, for instance, generally have smaller genomes than DNA viruses, a factor that contributes to their high mutation rates and...
Rab Cascades01:25

Rab Cascades

Rab GTPases act in a regulated cascade during membrane fusion, helping the lipid bilayers mix. The Rab family of proteins are active when bound to GTP, and inactive when bound to GDP. Hence, they act as guanine nucleotide-dependent molecular switches. Rab-GTP recognizes and binds to long or short-range tethering proteins to capture the target vesicle. These tethers coordinate with SNAREs on the vesicle and the target membrane to assemble the trans SNARE complex that locks the mixing bilayers.
Rous Sarcoma Virus (RSV) and Cancer01:03

Rous Sarcoma Virus (RSV) and Cancer

Rous Sarcoma virus or RSV was discovered by F. Peyton Rous in the year 1911 as a filterable transmissible agent that could cause tumors in chickens. He won a Nobel Prize for this discovery in 1966. His experiments clearly demonstrated that some cancers could be caused by infectious agents and led to the discovery of many more cancer-causing viruses in animals as well as humans.
RSV is a retrovirus that contains two copies of a plus-strand  RNA genome. Its genome consists of four main open...

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Related Experiment Video

Updated: May 29, 2026

Whole Genome Sequencing for Rapid Characterization of Rabies Virus Using Nanopore Technology
10:26

Whole Genome Sequencing for Rapid Characterization of Rabies Virus Using Nanopore Technology

Published on: August 18, 2023

[Rabies in Poland in 2009].

Małgorzata Sadkowska-Todys1, Bozena Kucharczyk

  • 1Zakład Epidemiologii Narodowego Instytutu Zdrowia Publicznego--Państwowego Zakładu Higieny w Warszawie. mtodys@pzh.gov.pl

Przeglad Epidemiologiczny
|September 15, 2011
PubMed
Summary

Poland reported a record low of 8 animal rabies cases in 2008, but wild animal reservoirs persist. In 2009, 6,366 people were vaccinated, primarily due to potential exposure to rabies.

Area of Science:

  • Veterinary Medicine
  • Epidemiology
  • Public Health

Context:

  • Poland documented a historic low of 8 animal rabies cases in 2008.
  • Despite the decline, wild animal rabies reservoirs remain, particularly in eastern Poland.
  • This indicates ongoing zoonotic disease surveillance needs.

Purpose:

  • To analyze rabies incidence in Poland in 2008.
  • To report on rabies post-exposure prophylaxis administration in 2009.
  • To identify primary drivers for rabies vaccination in humans.

Summary:

  • Animal rabies cases in Poland reached a record low of 8 in 2008.
  • In 2009, 6,366 individuals received rabies vaccinations.
  • The majority of vaccinations (89%) were a result of exposure to animals with unconfirmed rabies status.

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Evaluation of a Universal Nested Reverse Transcription Polymerase Chain Reaction for the Detection of Lyssaviruses
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Evaluation of a Universal Nested Reverse Transcription Polymerase Chain Reaction for the Detection of Lyssaviruses

Published on: May 2, 2019

A Trap-Vaccinate-Release Protocol for Immunization of Skunks and Additional Rabies Vectors Against Rabies
04:10

A Trap-Vaccinate-Release Protocol for Immunization of Skunks and Additional Rabies Vectors Against Rabies

Published on: November 29, 2024

Related Experiment Videos

Last Updated: May 29, 2026

Whole Genome Sequencing for Rapid Characterization of Rabies Virus Using Nanopore Technology
10:26

Whole Genome Sequencing for Rapid Characterization of Rabies Virus Using Nanopore Technology

Published on: August 18, 2023

Evaluation of a Universal Nested Reverse Transcription Polymerase Chain Reaction for the Detection of Lyssaviruses
08:10

Evaluation of a Universal Nested Reverse Transcription Polymerase Chain Reaction for the Detection of Lyssaviruses

Published on: May 2, 2019

A Trap-Vaccinate-Release Protocol for Immunization of Skunks and Additional Rabies Vectors Against Rabies
04:10

A Trap-Vaccinate-Release Protocol for Immunization of Skunks and Additional Rabies Vectors Against Rabies

Published on: November 29, 2024

Impact:

  • Highlights the success of rabies control programs in Poland.
  • Underscores the continued risk posed by wild animal rabies reservoirs.
  • Informs public health strategies for rabies prevention and post-exposure prophylaxis.