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Ablation of Ischemic Ventricular Tachycardia Using a Multipolar Catheter and 3-dimensional Mapping System for High-density Electro-anatomical Reconstruction
06:57

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Recovery of advanced atrioventricular block by cilostazol

Asami Nimura1, Nobuyuki Sato, Hitoshi Sakuragi

  • 1Cardiovascular Respiratory and Neurology Division, Department of Internal Medicine, Asahikawa Medical College, Japan.

Internal Medicine (Tokyo, Japan)
|September 17, 2011
PubMed

Insights

Cilostazol effectively restored atrioventricular (AV) conduction in a patient with advanced AV block. This oral medication reversed third-degree AV block, avoiding the need for a permanent pacemaker.

Area of Science:

  • Cardiology
  • Pharmacology

Background:

  • Advanced atrioventricular (AV) block necessitates interventions like permanent pacemaker implantation.
  • Third-degree AV block presents a critical condition affecting cardiac rhythm.

Observation:

  • A patient presented with advanced AV block, including third-degree AV block with intermittent AV synchrony for over two days.
  • The patient was evaluated for potential permanent pacemaker implantation.

Findings:

  • Oral administration of cilostazol at 200 mg/day led to complete recovery of AV conduction.
  • The treatment successfully reversed the advanced AV block without surgical intervention.

Implications:

  • Cilostazol may represent a novel therapeutic option for managing certain types of AV block.
  • Further research into the mechanism of cilostazol's effect on AV conduction is warranted.

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