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Updated: May 29, 2026

Multimodality Diagnosis of Mesenteric Ischemia
Published on: July 21, 2023
Superior mesenteric artery aneurysm: an uncommon disease with potentially serious complications
Ehab Akkary1, Tonya Cramer, Miral Patel
1Preston Memorial Hospital, Kingwood, WV, USA.
Abstract:
Superior mesenteric artery aneurysms (SMAAs) are visceral arterial aneurysms that can result from a variety of conditions. About half of SMAAs are mycotic and occur subsequent to infective endocarditis. The clinical presentation of SMAA is nonspecific, and some patients may be asymptomatic while others may report mild to severe abdominal pain. Herein, we present a case of a 53-year-old man who presented to the emergency department with abdominal pain 5 months after receiving medical treatment for infective endocarditis. CT scan demonstrated an aneurysm in the superior mesenteric artery and a splenic infarct. The patient underwent surgical excision with an uneventful recovery. Although rare, SMAAs are associated with a high risk of death secondary to rupture. They are difficult to detect through physical examination and the history is usually nonspecific. In this report we discuss the etiology of SMAA, diagnostic work-up and treatment options aiming for early diagnosis and management of this potentially fatal condition.
Insights
Superior mesenteric artery aneurysms (SMAAs), often linked to infective endocarditis, present nonspecific symptoms. Early diagnosis and surgical intervention are crucial for managing this rare but potentially fatal condition.
Area of Science:
- Vascular Surgery
- Infectious Diseases
- Abdominal Imaging
Background:
- Superior mesenteric artery aneurysms (SMAAs) are rare but life-threatening conditions.
- Mycotic aneurysms, often secondary to infective endocarditis, account for approximately half of SMAA cases.
- SMAAs present with nonspecific symptoms, ranging from asymptomatic to severe abdominal pain, complicating early detection.
Observation:
- A case report details a 53-year-old male presenting with abdominal pain post-infective endocarditis treatment.
- CT imaging revealed a superior mesenteric artery aneurysm and a splenic infarct in the patient.
- The patient successfully underwent surgical excision of the aneurysm with a favorable outcome.
Findings:
- SMAAs are associated with a high mortality rate due to rupture risk.
- Clinical diagnosis is challenging due to nonspecific symptoms and physical examination findings.
- This case highlights the importance of considering SMAA in patients with relevant medical history and abdominal symptoms.
Implications:
- Emphasizes the need for heightened clinical suspicion for SMAA in at-risk populations.
- Underscores the critical role of advanced imaging, such as CT scans, in diagnosing SMAA.
- Promotes timely surgical management to prevent catastrophic rupture and improve patient outcomes.
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