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Updated: May 29, 2026

Prostaglandin Extraction and Analysis in Caenorhabditis elegans
Published on: June 25, 2013
[Prostaglandin(PG) E2 in regulation of immunity and inflammatory diseases]
Rui Xue1, Yi-Fei Miao, Ji-Chun Yang
1Department of Physiology and Pathophysiology, Peking University Diabetes Center, Peking University Health Science Center, Beijing 100191, China.
Abstract:
Prostaglandin(PG) E2 is an important metabolic product of arachidonic acid. PGE2 plays important roles in regulation of fever, inflammatory responses and blood pressure via four functionally antagonistic E-prostanoid (EP) receptors, which are designated as EP1, EP2, EP3 and EP4, respectively. Recently, there is increasing evidence that PGE2 also regulates the maturation of immune cells and immune response. This review aims to briefly summarize and discuss the recent findings regarding the role of PGE2 in regulation of immunity.
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