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Updated: May 29, 2026

An Adipocyte Cell Culture Model to Study the Impact of Protein and Micro-RNA Modulation on Adipocyte Function
Published on: May 4, 2021
[Research progress in regulation of adiponectin receptors expression]
1Department of Physiology and Pathophysiology, Peking University Health Science Center, Key Laboratory of Molecular Cardiovascular Science, Ministry of Education, Beijing 100191, China.
Abstract:
Adiponectin is an adipokine mainly secreted by adipose tissue, which exerts insulin-sensitivity, anti-inflammation, anti-atherosclerosis and cardio-protective effects. These biological effects are mediated by adiponectin receptor 1 and adiponectin receptor 2. Expression levels of adiponectin receptor affect activation of downstream signaling pathway and biological effects. Research about regulation factors of adiponectin receptor expression contributes discovering the molecular mechanism and provides new ideas for the prevention and treatment of the metabolism disorder and cardiovascular diseases.
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