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The long noncoding RNA Six3OS acts in trans to regulate retinal development by modulating Six3 activity.

Nicole A Rapicavoli1, Erin M Poth, Heng Zhu

  • 1Department of Neuroscience, Neurology and Ophthalmology, Center for High-Throughput Biology and Institute for Cell Engineering, Johns Hopkins University School of Medicine, Baltimore, MD 21287, USA.

Neural Development
|September 23, 2011
PubMed
Summary

Six3OS, a long non-coding RNA, is crucial for retinal cell development by regulating Six3 activity. It acts as a scaffold to recruit histone modification enzymes, impacting neural development.

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