Related Experiment Video
Updated: May 29, 2026

Isolation and Identification of Waterborne Antibiotic-Resistant Bacteria and Molecular Characterization of their Antibiotic Resistance Genes
Published on: March 3, 2023
DDTRP: Database of Drug Targets for Resistant Pathogens
Jagadish Chandrabose Sundaramurthi1, Prabhakaran Ramanandan, Sridharan Brindha
1ICMR-Biomedical Informatics Centre, Tuberculosis Research Centre (ICMR), Chetpet, Chennai-600031, Tamil Nadu, India.
Abstract:
Emergence of drug resistance is a major threat to public health. Many pathogens have developed resistance to most of the existing antibiotics, and multidrug-resistant and extensively drug resistant strains are extremely difficult to treat. This has resulted in an urgent need for novel drugs. We describe a database called 'Database of Drug Targets for Resistant Pathogens' (DDTRP). The database contains information on drugs with reported resistance, their respective targets, metabolic pathways involving these targets, and a list of potential alternate targets for seven pathogens. The database can be accessed freely at http://bmi.icmr.org.in/DDTRP.
Related Concept Videos
Therapeutic Drug Monitoring: Drug Analysis Methods
Targets for Drug Action: Overview
Receptors are either membrane-spanning or intracellular proteins, which upon binding a ligand, get activated and transmit the signal downstream to elicit a response. Drugs bind receptors, either mimicking the action of endogenous ligands or blocking the receptor activity to bring about a modified response. Nearly 35% of approved drugs target the G...
Development of Antibiotic Resistance
Therapeutic Drug Monitoring: Overview and Classification
Pharmacogenomics: Identification of New Drug Targets
Treatment Resistant Cancers
