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Updated: May 29, 2026

A Comparative Study of Drug Delivery Methods Targeted to the Mouse Inner Ear: Bullostomy Versus Transtympanic Injection
Published on: March 8, 2017
[Synergic effect of alprostadil injection and ginaton in treating sudden deafness]
Jiping Jiang1, Shuyun Wang, Kang Tong
1Department of Otorhinolaryngology-Head and Neck Surgery, 305 Hospital, Beijing, 100017, China. 305jiangjiping@163.com
Objective:
To explore synergic effect of Alprostadil injection and ginaton in treating sudden deafness.
Method:
ninety one patients with sudden deafness were divided into group A, group B and group C at random; 33 ears of group A were treated with 70 mg ginaton by vein, 30 ears of group B were treated with 10 microg Alprostadil injection by vein, 31 ears of group C were treated with 10 microg Alprostadil injection and ginaton by vein,once a day, the time of treatment is 14 days.
Result:
the effective rate of group A is 60.61%, the effective rate of group B is 60.00%, the effective rate of group C is 87.09% the treating effect was significantly different in the group A and C (P < 0.05), it was significantly different in the group B and C (P < 0.05)).
Conclusion:
It is effective for Alprostadil injection and ginaton to treat sudden deafness, and it has significantly Synergic effect in treating sudden deafness with Alprostadil injection and ginaton.
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