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Related Concept Videos

Ethics in Research01:56

Ethics in Research

Today, scientists agree that good research is ethical in nature and is guided by a basic respect for human dignity and safety. However, this has not always been the case. Modern researchers must demonstrate that the research they perform is ethically sound.
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Embryonic stem (ES) cells were first discovered in mice in 1981 by Martin Evans. In 1998, James Thomson identified a method to isolate embryonic stem cells from humans. Human embryonic stem cells (hESCs) are obtained from 3-5 day old embryos that remain unused after an in vitro fertilization procedure.
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Working with Human Tissues for Translational Cancer Research
07:48

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Published on: November 26, 2015

Moving human SCNT research forward ethically.

Insoo Hyun1

  • 1Department of Bioethics, Case Western Reserve University School of Medicine, Cleveland, OH 44106-4976, USA. insoo.hyun@case.edu

Cell Stem Cell
|October 11, 2011
PubMed
Summary
This summary is machine-generated.

Human somatic cell nuclear transfer (SCNT) research is advancing, requiring careful consideration of ethical egg procurement. Stringent ethical standards are imperative for future stem cell research involving directed egg donation.

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Area of Science:

  • Reproductive biology
  • Stem cell science
  • Bioethics

Background:

  • Somatic cell nuclear transfer (SCNT) is a technique used to create cloned embryos.
  • Recent advancements in reprogramming human somatic cells to pluripotency via SCNT necessitate a re-evaluation of related ethical considerations.
  • Human egg procurement is a critical component of SCNT research.

Purpose of the Study:

  • To highlight the renewed interest in human egg procurement driven by SCNT advancements.
  • To emphasize the need for ethical guidelines in human SCNT research.
  • To advocate for ethical practices in directed egg donation for stem cell research.

Main Methods:

  • The study reviews recent advancements in human somatic cell reprogramming via SCNT.
  • Ethical considerations surrounding human egg procurement are discussed.
  • The importance of ethical standards in research locales permitting directed egg donation is examined.

Main Results:

  • Recent SCNT studies have renewed interest in human egg procurement.
  • Ethical standards must be stringent for human SCNT research.
  • Directed egg donation for stem cell research requires careful ethical oversight.

Conclusions:

  • Human SCNT research necessitates robust ethical frameworks.
  • Ethical egg procurement is crucial for advancing stem cell therapies.
  • Oversight of directed egg donation is essential for responsible SCNT research.