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Lineage plasticity driven by GATA6 loss fuels colorectal cancer metastasis

Saori Goto1, Vikram Deshpande2, Ömer H Yilmaz3

  • 1Joan and Sanford I. Weill Department of Medicine, Division of Gastroenterology and Hepatology, Weill Cornell Medicine, Cornell University, New York, NY, USA; Jill Roberts Institute for Research in Inflammatory Bowel Disease, Weill Cornell Medicine, Cornell University, New York, NY, USA; Department of Biology, The David H. Koch Institute for Integrative Cancer Research at MIT, Massachusetts Institute of Technology, Cambridge, MA 02139, USA.

Cell Stem Cell
|June 22, 2026
PubMed
Abstract

Keywords:
colorectal cancermetastasisorganoid

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