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A Caenorhabditis elegans Nutritional-status Based Copper Aversion Assay
Published on: July 26, 2017
Is the Western diet adequate in copper?
1Department of Internal Medicine, University of North Dakota, School of Medicine and Health Sciences, Grand Forks, ND 58201, United States. leslie.klevay@und.edu
Copper is essential for health, but Western diets provide less than recommended amounts. Increasing identification of copper deficiency suggests potential links to serious diseases like Alzheimer's and heart disease.
Area of Science:
- Human Nutrition
- Biochemistry
Background:
- Copper is an essential trace element vital for numerous physiological functions.
- Dietary copper intake has declined significantly in Western populations since the 1930s.
- Suboptimal copper levels are increasingly recognized, impacting various bodily systems.
Purpose of the Study:
- To review the evidence on copper deficiency in human health.
- To highlight the prevalence of low copper intake and its potential health consequences.
- To discuss the link between copper nutriture and chronic diseases.
Main Methods:
- Review of existing literature on copper metabolism and deficiency.
- Analysis of dietary intake trends and recommended allowances.
- Examination of clinical reports and controlled trials involving copper supplementation.
Main Results:
- A significant portion of adults in Europe, the UK, US, and Canada consume less than adequate copper.
- Hundreds of individuals have been identified with impaired copper nutriture.
- Controlled trials show benefits of copper supplementation in nearly 1000 participants.
Conclusions:
- Copper deficiency is an emerging health concern with widespread implications.
- Low copper intake is increasingly identified and may contribute to conditions like Alzheimer's disease, ischemic heart disease, and osteoporosis.
- Further research is needed to understand the causes and full impact of copper deficiency.
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