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Updated: May 28, 2026
10:34
Double Direct Injection of Blood into the Cisterna Magna as a Model of Subarachnoid Hemorrhage
Published on: August 30, 2020
Risk factors related to aneurysmal rebleeding
Lie-Mei Guo1, Hong-Yu Zhou, Ji-Wen Xu
1Department of Neurosurgery, Renji Hospital, Shanghai Jiao Tong University, Shanghai, China.
World Neurosurgery
|October 12, 2011
Summary
Rebleeding from ruptured intracranial aneurysms is common within 72 hours of initial SAH. Advanced age, larger aneurysm size, high blood pressure, and severe Hunt-Hess grade are key risk factors for rebleeding.
Area of Science:
- Neurosurgery
- Neurology
- Vascular Neurology
Background:
- Rebleeding from ruptured intracranial aneurysms significantly increases mortality and disability.
- Early intervention is crucial to prevent rebleeding and improve patient outcomes.
Purpose of the Study:
- To determine the incidence of rebleeding in patients with aneurysmal subarachnoid hemorrhage (SAH).
- To identify independent risk factors associated with rebleeding prior to early aneurysm repair.
Main Methods:
- Retrospective collection of demographic and clinical data from 326 patients with aneurysmal SAH.
- Univariate and binary logistic regression analyses were performed to identify risk factors for rebleeding.
Main Results:
- Rebleeding occurred in 21.5% of patients within 72 hours of SAH, with most events happening within 6 hours.
- Independent risk factors for rebleeding included advanced age (OR=1.167), larger aneurysm size (OR=1.624), elevated systolic blood pressure (SBP) (OR=3.338), and higher Hunt-Hess grade (OR=2.512).
Conclusions:
- Early aneurysmal rebleeding is a significant concern in the hours following SAH.
- Factors such as older age, large aneurysm size (>10 mm), high SBP (>160 mmHg), and poor Hunt-Hess grade predict rebleeding risk.
- Emphasizing prompt aneurysm repair is vital due to the poor outcomes associated with rebleeding.
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