Iron deficiency in children with attention deficit hyperactivity disorder
Eli Lahat1, Eli Heyman, Amir Livne
1Pediatric Neurology Unit, Asaf Harofeh Medical Center, Zerifin, Israel. elahat@asaf.health.gov.il
The Israel Medical Association Journal : IMAJ
|October 14, 2011
Summary
Many children with Attention Deficit Hyperactivity Disorder (ADHD) have low iron stores. This study suggests evaluating ferritin levels in children diagnosed with ADHD to assess iron deficiency.
Area of Science:
- Pediatric Neurology
- Nutritional Psychiatry
Background:
- Iron is crucial for neurotransmitter synthesis, including dopamine and noradrenaline.
- Iron deficiency is hypothesized to play a role in the pathophysiology of Attention Deficit Hyperactivity Disorder (ADHD).
Purpose of the Study:
- To assess iron deficiency in children with ADHD using serum ferritin levels.
- To explore the correlation between ferritin levels and ADHD diagnosis.
Main Methods:
- The study included 113 newly referred children diagnosed with ADHD, aged 5-15 years.
- Serum ferritin levels were measured as an indicator of iron storage.
Main Results:
- 59% of ADHD children (67 out of 113) exhibited ferritin levels below 20 ng/ml.
- A weak inverse correlation was observed between Conners' Rating Scale scores and ferritin levels, lacking clinical significance.
Conclusions:
- Low iron stores are potentially linked to ADHD pathophysiology.
- Ferritin level assessment should be considered in the comprehensive evaluation of children with ADHD.
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