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Obesity01:24

Obesity

The Body Mass Index (BMI) is a numerical value derived from a person's weight and height, used to categorize individuals into weight ranges. It is calculated using the formula: weight in kilograms divided by height in meters squared. Obesity is a health condition characterized by excessive accumulation of adipose tissue that poses health risks, often diagnosed with a BMI ≥ 30. This excess fat storage occurs when surplus dietary calories are converted into triglycerides and stored in adipocytes...
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Drug Dosing: Obese Patients

In the United States, obesity is a prominent concern. It is linked to heightened mortality rates due to increased occurrences of conditions such as hypertension, atherosclerosis, coronary artery disease, and diabetes compared to nonobese individuals. A patient is classified as obese if their actual body weight surpasses the ideal or desirable body weight by 20%, based on Metropolitan Life Insurance Company data. Ideal body weights consider average weights and heights for males and females...
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Drug metabolism, a critical process in the liver, involves two primary phases: Phase I reactions and Phase II conjugation. Obesity introduces significant alterations in this metabolic process, primarily due to fatty infiltration of the liver, leading to conditions such as nonalcoholic fatty liver disease (NAFLD). This condition can modify the activities of both Phase I and II enzymes, impacting how drugs are metabolized in obese patients.Phase I metabolism sees variable effects across...
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The hypodermis (the subcutaneous layer or superficial fascia) is present directly below the dermis. It connects the skin to the underlying fascia (fibrous tissue) of the bones and muscles. It is not strictly a part of the skin, although the border between the hypodermis and dermis can be difficult to distinguish. The hypodermis consists of well-vascularized, loose, areolar connective tissue and adipose tissue, which functions as a mode of fat storage and provides insulation and cushioning for...
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Related Experiment Video

Updated: May 28, 2026

Segmentation and Measurement of Fat Volumes in Murine Obesity Models Using X-ray Computed Tomography
13:09

Segmentation and Measurement of Fat Volumes in Murine Obesity Models Using X-ray Computed Tomography

Published on: April 4, 2012

Obesity in the paleolithic era.

Laszlo G Jozsa1

  • 1Department of Pathology, National Institute of Traumatology, Budapest, Hungary. jozsalg@gmail.hu

Hormones (Athens, Greece)
|October 18, 2011
PubMed
Summary

Upper Paleolithic figurines reveal diverse female body types, with over half depicting overweight or obese individuals, challenging the fertility-focused interpretation of Venus idols.

Area of Science:

  • Paleoanthropology
  • Archaeology
  • Art History

Background:

  • The Upper Paleolithic period (45,000-40,000 to 10,000 BP) is known for its portable art, including numerous female figurines often termed 'Venus' idols.
  • These artifacts are frequently interpreted as symbols of fertility and reproduction.

Observation:

  • A study analyzed 100 Upper Paleolithic statues, focusing on 97 female figurines from multiple views.
  • Body types varied, with 24 figurines representing slender individuals, 15 normal weight, and 51 overweight or obese.
  • Specific fat distribution patterns were noted, including steatopygia (excessive buttocks fat) in 7 figurines, independent of overall body weight.

Findings:

  • Over half of the studied female figurines depicted overweight or obese body types, with significant fat deposition in various areas like the belly, hips, buttocks, and femora.

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  • Only seven figurines showed signs of advanced pregnancy, contradicting the common assumption that all Venus idols represent fertility.
  • Steatopygia was observed in some figurines that were otherwise not significantly overweight, suggesting a specific aesthetic or cultural emphasis.
  • Implications:

    • The diversity in body representation suggests that Upper Paleolithic figurines may have served multiple symbolic purposes beyond fertility, potentially including social status, health, or aesthetic ideals.
    • Rethinking the interpretation of Venus figurines is necessary, moving beyond a singular focus on reproduction to encompass a broader range of meanings.
    • The prevalence of diverse body types in Upper Paleolithic art offers insights into the perceptions and values of ancient societies regarding the female form.