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Updated: May 28, 2026

Rapid Nanoprobe Signal Enhancement by In Situ Gold Nanoparticle Synthesis
Published on: March 7, 2018
Ultrasensitive and selective colorimetric detection of thiourea using silver nanoprobes
Guang-Li Wang1, Yu-Ming Dong, Xiao-Ying Zhu
1School of Chemical and Material Engineering, Jiangnan University, Wuxi, PR China. glwang@jiangnan.edu.cn
Abstract:
A novel colorimetric thiourea (TU) sensor was developed utilizing citrate modified silver nanoparticles (AgNPs). The introduction of TU reduced the overall surface charges of the AgNPs, resulting in aggregation of AgNPs and a colorimetric response correlating with the concentration of TU. The detection of TU could be realized within 2 min, with an ultralow detection limit of 0.8 nM by the absorption method. In addition, the AgNPs sensor also showed good selectivity in the presence of potential interfering compounds. Since common steps such as modification and separation could be successfully avoided, the sensor developed here could provide a simple, cost-effective yet rapid and sensitive measurement tool for TU detection, and may provide new opportunities in the development of sensors for food safety and environmental monitoring in the future.
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