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Giant stomach secondary to juvenile polyposis syndrome

Nathalie Wong-Chong1, Wondwossen Hailu Kidanewold, Richard Kirsch

  • 1Department of Surgery, Mount Sinai Hospital, 600 University Avenue, Suite 1225, Toronto, ON, M5G 1X5, Canada.

Journal of Gastrointestinal Surgery : Official Journal of the Society for Surgery of the Alimentary Tract
|October 19, 2011
PubMed

Insights

Juvenile polyposis syndrome (JPS) can cause massive gastric polyposis, leading to severe complications. This case highlights the need for timely intervention, including total gastrectomy, for life-threatening JPS manifestations.

Area of Science:

  • Gastroenterology
  • Genetics
  • Pathology

Background:

  • Juvenile polyposis syndrome (JPS) is a rare autosomal dominant disorder.
  • Typically, polyps affect the colon, but gastric and small intestine involvement can occur.

Observation:

  • A 27-year-old woman presented with severe anemia and severe gastric polyposis.
  • The condition progressed over 5 years, causing hematemesis, hypoproteinemia, and gastric outlet obstruction.

Findings:

  • Histopathology confirmed juvenile polyposis.
  • Massive gastric polyposis led to severe gastromegaly (stomach enlargement).

Implications:

  • This case demonstrates an unusual presentation of JPS with severe gastric involvement.
  • Total gastrectomy was necessary to manage life-threatening complications of massive gastric polyposis.
Abstract

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