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Updated: May 28, 2026

Characterization of Inflammatory Responses During Intranasal Colonization with Streptococcus pneumoniae
Published on: January 17, 2014
[Microbial profile and antibiotic susceptibility of chronic rhinosinusitis]
Lizhi Xiao1, Jing Zheng, Lei Yang
1Department of Otolaryngology Head and Neck Surgery, the First Affiliated Hospital of Guangzhou Medical College, Guangzhou, 510120, China.
Objective:
To investigate distribution and drug-susceptibility of bacteria in patients with chronic rhinosinusitis.
Method:
The purulent discharges or mucous membrane lesions were collected from the sinus of 51 patients with chronic rhinosinusitis receiving sinus surgery. The clinical specimens were incubated and the drug susceptibility was analyzed.
Result:
Of 51 specimens, 41 (80.39%) showed positive results in bacteria culture. The antibiotic susceptibility was as follows: vancomycin-100%, moxifloxacin-100%, levofloxacin-92.31%, rifampin-90.91%, ciprofloxacin-81.58%, SMZ-TMP-67.65%, azithromycin-47.62%, clarithromycin-45.00%, ampicillin sodium and sulbactam sodium-35.90%, cefatriaxone-39.39%, cefuroxime sodium-30.43%, penicillin-8.33%.
Conclusion:
There are bacteria infections in most of chronic rhinosinusitis. The fluoroquinolones should be preferred in sinus surgery.
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