Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Sources of Food Contamination01:29

Sources of Food Contamination

Contamination of food by microbial agents and natural toxins poses significant risks to public health. These hazards can be introduced at various points across the food supply chain, ranging from environmental sources to processing and storage stages. Understanding these contamination pathways is critical for developing strategies to ensure food safety.Seafood is particularly vulnerable to contamination through both environmental exposure and microbial colonization. Toxins from harmful algal...
Toxoplasmosis01:28

Toxoplasmosis

Toxoplasmosis, a zoonotic disease caused by the protozoan Toxoplasma gondii, poses significant public health challenges globally due to its high seroprevalence and varied clinical manifestations. As an obligate intracellular parasite, T. gondii can infect all warm-blooded vertebrates, but felids are its only definitive hosts, shedding unsporulated oocysts into the environment. Humans typically acquire the infection through ingestion of tissue cysts in undercooked meat or oocysts from...
Pasteurization and Food Preservation01:28

Pasteurization and Food Preservation

Pasteurization is a widely employed thermal processing technique designed to enhance the safety and shelf life of perishable food and beverages. By subjecting products to specific high temperatures for controlled durations, this method effectively inactivates pathogenic microorganisms and spoilage enzymes without significantly compromising sensory qualities. The technique has been pivotal in food safety management, especially for consumables susceptible to microbial contamination such as milk,...
Tuberculosis01:23

Tuberculosis

Tuberculosis (TB) remains a significant global health concern, primarily targeting the lungs and spreading through airborne transmission. Infection begins when aerosolized droplet nuclei, expelled by an individual with active TB, are inhaled by another person. These microscopic particles carry Mycobacterium tuberculosis, the causative agent of TB. Upon reaching the alveoli, the bacilli are engulfed by alveolar macrophages. However, due to their specialized lipid-rich cell wall, these pathogens...
Pulmonary Tuberculosis I01:29

Pulmonary Tuberculosis I

Tuberculosis, often called TB, is a contagious illness primarily caused by Mycobacterium tuberculosis. It mainly affects the lung parenchyma but can also impact other body parts.
Causative Organism
The primary infectious agent causing tuberculosis is Mycobacterium tuberculosis, a slow-growing, acid-fast, aerobic rod that exhibits sensitivity to heat and ultraviolet light. Instances of Mycobacterium bovis and Mycobacterium avium contributing to the development of TB infection are rare.
Mode of...
Pulmonary Tuberculosis III01:31

Pulmonary Tuberculosis III

Tuberculosis (TB) is a contagious infection primarily affecting the lung parenchyma but which can also affect other body parts. TB can be classified based on disease development, presentation, and the affected anatomical site.
The first classification is based on the development of the disease, and it includes the following categories:

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Bone and Radiologic Findings in Congenital Generalized Lipodystrophy: A Systematic Review and Report of 60 Cases.

Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research·2026
Same author

Gα<sub>s</sub> variant detection discerns skeletal cell types involved in fibrous dysplasia pathogenesis.

Bone·2026
Same author

Fibrous dysplasia/McCune-Albright syndrome: state-of-the-art advances, pathogenesis, and basic/translational research.

Orphanet journal of rare diseases·2025
Same author

Best practice recommendations for the diagnosis and management of hypoparathyroidism.

Metabolism: clinical and experimental·2025
Same author

A mouse model of Jansen's metaphyseal chondrodysplasia for investigating disease mechanisms and candidate therapeutics.

Proceedings of the National Academy of Sciences of the United States of America·2025
Same author

Pain in fibrous dysplasia: identifying nociceptive mechanisms in a preclinical model.

Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research·2025

Related Experiment Video

Updated: May 28, 2026

Development of an Electrochemical DNA Biosensor to Detect a Foodborne Pathogen
17:16

Development of an Electrochemical DNA Biosensor to Detect a Foodborne Pathogen

Published on: June 3, 2018

Food safety concerns regarding paratuberculosis.

Michael T Collins1

  • 1Department of Pathobiological Sciences, School of Veterinary Medicine, University of Wisconsin, 2015 Linden Drive, Madison, WI 53706-1102, USA. mcollin5@wisc.edu

The Veterinary Clinics of North America. Food Animal Practice
|October 26, 2011
PubMed
Summary

Mycobacterium avium subsp. paratuberculosis (MAP) resists food processing, potentially linking it to Crohn's disease. Controlling Johne's disease in animals is crucial to reduce human exposure risks from contaminated foods.

More Related Videos

Adjuvant Activity of Mycobacterium paratuberculosis in Enhancing the Immunogenicity of Autoantigens During Experimental Autoimmune Encephalomyelitis
06:57

Adjuvant Activity of Mycobacterium paratuberculosis in Enhancing the Immunogenicity of Autoantigens During Experimental Autoimmune Encephalomyelitis

Published on: May 12, 2023

Environmental Screening of Aeromonas hydrophila, Mycobacterium spp., and Pseudocapillaria tomentosa in Zebrafish Systems
09:58

Environmental Screening of Aeromonas hydrophila, Mycobacterium spp., and Pseudocapillaria tomentosa in Zebrafish Systems

Published on: December 8, 2017

Related Experiment Videos

Last Updated: May 28, 2026

Development of an Electrochemical DNA Biosensor to Detect a Foodborne Pathogen
17:16

Development of an Electrochemical DNA Biosensor to Detect a Foodborne Pathogen

Published on: June 3, 2018

Adjuvant Activity of Mycobacterium paratuberculosis in Enhancing the Immunogenicity of Autoantigens During Experimental Autoimmune Encephalomyelitis
06:57

Adjuvant Activity of Mycobacterium paratuberculosis in Enhancing the Immunogenicity of Autoantigens During Experimental Autoimmune Encephalomyelitis

Published on: May 12, 2023

Environmental Screening of Aeromonas hydrophila, Mycobacterium spp., and Pseudocapillaria tomentosa in Zebrafish Systems
09:58

Environmental Screening of Aeromonas hydrophila, Mycobacterium spp., and Pseudocapillaria tomentosa in Zebrafish Systems

Published on: December 8, 2017

Area of Science:

  • Food safety and microbiology
  • Veterinary epidemiology
  • Zoonotic disease research

Background:

  • Contamination of animal-derived foods with Mycobacterium avium subsp. paratuberculosis (MAP) occurs frequently during both ante mortem and post mortem stages.
  • MAP exhibits innate resistance to heat and other physical processing methods, rendering standard food manufacturing practices insufficient for its elimination.
  • The zoonotic potential of MAP and its association with human diseases, particularly Crohn's disease, remains a subject of ongoing medical investigation.

Purpose of the Study:

  • To highlight the challenges in eliminating Mycobacterium avium subsp. paratuberculosis (MAP) from foods of animal origin.
  • To discuss the potential link between MAP exposure and human health conditions like Crohn's disease.
  • To emphasize the importance of on-farm biosecurity measures for Johne's disease control in livestock.

Main Methods:

  • Review of existing literature on Mycobacterium avium subsp. paratuberculosis (MAP) contamination in food products.
  • Analysis of MAP's resistance to common food processing techniques.
  • Examination of epidemiological data regarding MAP presence in humans and its correlation with Crohn's disease.

Main Results:

  • Standard food manufacturing processes are ineffective in eradicating Mycobacterium avium subsp. paratuberculosis (MAP) due to its resilience.
  • A significant number of individuals with Crohn's disease show evidence of MAP, suggesting a potential etiological connection.
  • The debate continues within the medical community regarding the definitive human health impacts of MAP exposure.

Conclusions:

  • Effective control of Mycobacterium avium subsp. paratuberculosis (MAP) in food requires addressing its presence in the primary animal reservoir.
  • Implementing on-farm measures to manage Johne's disease in livestock is a critical strategy to minimize potential human exposure to MAP.
  • Further research is warranted to fully elucidate the zoonotic implications of MAP and its role in human inflammatory bowel diseases.