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Published on: August 27, 2021
BioRadioTransmitter: a self-powered wireless glucose-sensing system
Takuya Hanashi1, Tomohiko Yamazaki, Wakako Tsugawa
1Department of Biotechnology, Graduate School of Engineering, Tokyo University of Agriculture and Technology, Tokyo, Japan.
Journal of Diabetes Science and Technology
|October 27, 2011
Summary
This study introduces the BioRadioTransmitter, a self-powered wireless glucose sensor. It uses a novel capacitor-based biosensor and enzyme fuel cell to transmit glucose concentration wirelessly, advancing continuous glucose monitoring.
Area of Science:
- Biomedical Engineering
- Biosensors
- Implantable Devices
Background:
- Enzyme fuel cells (EFCs) offer glucose sensing but lack sufficient power for wireless transmission.
- External power sources are typically required for EFC-based biosensing systems.
- A novel BioCapacitor biosensor utilizing a capacitor as a transducer was proposed.
Purpose of the Study:
- To develop a self-powered, wireless glucose sensing system.
- To integrate a miniaturized enzyme fuel cell with a radio transmitter circuit.
- To overcome the power limitations of traditional EFC glucose sensors.
Main Methods:
- Constructed a direct-electron-transfer-type, compartmentless enzyme fuel cell with specific anode and cathode materials.
- Integrated the enzyme fuel cell with a capacitor, charge-pump IC, and Hartley oscillator for wireless transmission.
- Developed a radio receiver to amplify and process signals from the BioRadioTransmitter.
Main Results:
- Successfully transmitted radio wave signals wirelessly from the BioRadioTransmitter.
- Demonstrated that radio wave transmission frequency changes correlate with glucose concentration.
- Achieved signal reception, amplification, and conversion by the radio receiver.
Conclusions:
- Developed a stand-alone, self-powered wireless glucose-sensing system named BioRadioTransmitter.
- The system's radio wave transmission frequency is modulated by glucose concentration.
- Represents a significant advancement for implantable continuous glucose monitoring systems.

