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Simultaneous immunoassay for the detection of two lung cancer markers using functionalized SERS nanoprobes
Hyangah Chon1, Sangyeop Lee, Soo-Young Yoon
1Department of Bionano Engineering, Hanyang University, Ansan 426-791, South Korea.
Chemical Communications (Cambridge, England)
|October 27, 2011
Abstract:
A quick and reproducible SERS-based immunoassay, using functionalized hollow gold nanospheres and magnetic beads, has been developed. Here, a simultaneous detection of dual cancer markers in blood serum has been achieved under a single excitation wavelength. The accuracy and sensitivity for clinical sera from five patients confirms their diagnostic feasibility.
