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Curvularia/Drechslera sinusitis.

S M Killingsworth1, S J Wetmore

  • 1Department of Otolaryngology-Head & Neck Surgery, University of Arkansas for Health Sciences, Little Rock.

The Laryngoscope
|September 1, 1990
PubMed
Summary
This summary is machine-generated.

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Unusual fungal sinusitis can affect healthy adults, causing serious complications like vision loss and seizures. Early diagnosis and aggressive surgical treatment are crucial for recovery.

Area of Science:

  • Mycology
  • Infectious Diseases
  • Otolaryngology

Background:

  • Fungal sinusitis is typically associated with immunocompromised individuals.
  • Uncommon fungal pathogens can cause sinusitis in immunocompetent hosts.

Observation:

  • Three cases of sinusitis caused by Curvularia and Drechslera in healthy young adults are presented.
  • Symptoms included decreased visual acuity and acute onset of seizures.
  • Computed tomography (CT) scans aided in disease assessment and treatment monitoring.

Findings:

  • Aggressive surgical intervention is essential for managing invasive fungal sinusitis.
  • Two of the three reported cases required repeat surgeries for complete disease eradication.
  • Histopathological confirmation of fungal invasion warrants intravenous amphotericin B treatment.

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Implications:

  • Clinicians should consider fungal cultures and smears in healthy patients presenting with sinusitis complications.
  • Prompt and aggressive management can lead to favorable outcomes even in severe cases.
  • This highlights the importance of considering non-invasive fungal sinusitis in immunocompetent individuals.