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Updated: May 28, 2026

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Harmonic focus in total thyroidectomy plus level III-IV and VI dissection: a prospective randomized study.

Qingqing He1, Dayong Zhuang, Luming Zheng

  • 1Department of Thyroid and Breast Surgery, Jinan Military General Hospital, Jinan, People's Republic of China. heqingqing@yeah.net

World Journal of Surgical Oncology
|November 2, 2011
PubMed
Summary
This summary is machine-generated.

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The Harmonic Focus device significantly reduces operating time and drainage volume during total thyroidectomy with neck dissection compared to traditional suture ligation. This advanced technique proves safe and effective for thyroid vessel control.

Area of Science:

  • Surgical Oncology
  • Endocrine Surgery

Background:

  • Total thyroidectomy with neck dissection is a standard procedure for thyroid cancer.
  • Hemostasis during thyroid surgery is crucial for minimizing complications.
  • Traditional suture ligation is time-consuming and can increase operative time.

Purpose of the Study:

  • To compare the Harmonic Focus no-tie technique with classic suture ligation for hemostasis in total thyroidectomy plus level III-IV and VI dissection.
  • To evaluate differences in operating time, postoperative outcomes, and surgical complications between the two techniques.

Main Methods:

  • A comparative study involving 105 patients undergoing total thyroidectomy plus level III-IV and VI dissection.
  • Group 1: 54 patients using classic suture ligation.
  • Group 2: 51 patients using the Harmonic Focus no-tie technique.

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Main Results:

  • The Harmonic Focus group had significantly shorter operating times (102.8 minutes) compared to the classic group (150.1 minutes).
  • Drainage volume was significantly lower in the Harmonic Focus group (202.7 mL) versus the classic group (299.7 mL).
  • No statistically significant difference in transient hypoparathyroidism rates (17.6% vs 18.5%). No nerve injury or permanent hypocalcemia observed in either group.

Conclusions:

  • The Harmonic Focus no-tie technique is a reliable and safe alternative for controlling thyroid vessels during thyroid surgery.
  • This device offers advantages in reducing operative time and postoperative drainage, enhancing surgical efficiency.