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Updated: May 28, 2026

Tissue Engineering of the Intestine in a Murine Model
Published on: December 1, 2012
[Gastrointestinal bleeding and intussusception caused by Peutz-Jeghers syndrome]
Elisabeth Christiansen1, Rasmus Nielsen
1Pædiatisk Afdeling, Kolding Sygehus, 6000 Kolding, Denmark. elisabeth_christiansen@yahoo.dk
Abstract:
Peutz-Jeghers syndrome (PJS) is an inherited, autosomal dominant disorder characterised by haematomatous polyps in the gastrointestinal tract and mucocutaneus hyperpigmentation. A girl 15 years of age presented with microcytic, hypochrome anaemia. Endoscopy revealed several polyps in the stomach and colon. The patient was later operated due to an intussusception from polyps in the jejunum. Histology proved the polyps to be haematomatous as seen in PJS. Patients with PJS have an increased risk of developing both gastrointestinal and extra-gastrointestinal cancers. Screening recommendation for PJS is outlined.
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