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Updated: May 28, 2026

Quantification of Tumor Cell Adhesion in Lymph Node Cryosections

Quantification of Tumor Cell Adhesion in Lymph Node Cryosections

Published on: February 9, 2020

Lymphadenectomy in urologic oncology: pathologic considerations.

Riley E Alexander¹, Ming-Tse Sung, Liang Cheng

¹Department of Pathology and Laboratory Medicine, Indiana University School of Medicine, Room 4010, 350 West 11th Street, Indianapolis, IN 46202, USA.

The Urologic Clinics of North America

|November 3, 2011

Summary

Optimal oncologic surgery requires effective lymphadenectomy (LAD) staging and treatment. This review details pathologic evaluation and urologist-pathologist communication for genitourinary malignancies, offering specimen handling recommendations.

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Area of Science:

Urologic Oncology
Pathology
Surgical Oncology

Background:

Lymphadenectomy (LAD) is crucial for staging and treating genitourinary (GU) cancers.
GU cancer lymphadenectomy presents unique challenges due to anatomical and histological variations.
Effective communication between urologists and pathologists is vital for patient care.

Purpose of the Study:

To review current practices in the pathologic evaluation of lymphadenectomy specimens in GU malignancies.
To provide recommendations for specimen submission, processing, and interpretation.
To highlight emerging prognostic markers and molecular techniques in GU cancer pathology.

Main Methods:

Literature review focusing on lymphadenectomy in GU oncology.
Analysis of challenges in GU cancer pathology.

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Last Updated: May 28, 2026

Quantification of Tumor Cell Adhesion in Lymph Node Cryosections

Quantification of Tumor Cell Adhesion in Lymph Node Cryosections

Published on: February 9, 2020

Discussion of interdisciplinary communication strategies.

Inclusion of specific recommendations for various GU sites (kidney, bladder, prostate, etc.).

Main Results:

Lymphadenectomy evaluation in GU malignancies requires tailored approaches.
Standardized specimen handling and clear communication enhance diagnostic accuracy.
Molecular techniques are increasingly important for prognostic assessment.

Conclusions:

Improved communication and standardized pathologic evaluation are essential for optimal lymphadenectomy in GU oncology.
Specific guidelines for different GU sites improve specimen assessment.
Emerging molecular diagnostics offer new prognostic insights.